中国媒介生物学及控制杂志 ›› 2011, Vol. 22 ›› Issue (2): 198-200.

• 综述 • 上一篇    

转基因蚊的抗疟研究

代玉华, 张本光, 魏继波, 公茂庆   

  1. 山东省寄生虫病防治研究所医学昆虫学部,山东省医学科学院,山东 济宁 272033
  • 收稿日期:2010-12-09 出版日期:2011-04-20 发布日期:2011-04-20
  • 通讯作者: 公茂庆,Email: maoqingg@yahoo.com
  • 作者简介:代玉华(1977-),女,博士,助理研究员,从事媒介生物学研究。Email: dai_yuhua@yahoo.com.cn
  • 基金资助:

    山东省科技攻关项目(2010GWZ20234)

Advances in the research on transgenic anti-malaria mosquito

DAI Yu-hua, ZHANG Ben-guang, WEI Ji-bo, GONG Mao-qing   

  1. Shandong Institute of Parasitic Diseases, Shandong Academy of Medical Sciences, Jining 272033, Shandong Province, China
  • Received:2010-12-09 Online:2011-04-20 Published:2011-04-20
  • Supported by:

    Supported by the Shandong Province Science and Technology Projects (No. 2010GWZ20234)

摘要:

疟疾每年造成近百万人死亡,随着蚊虫抗药性的增加,导致现有抗疟策略的效率降低。转基因蚊研究为抗疟提供了新的途径,成为防治疟疾的新方法。现将转基因技术在蚊虫中的应用、基因调控机制以及转基因蚊发挥作用的途径等做一综述。

关键词: 转基因蚊, 疟疾, 机制

Abstract:

Malaria (Plasmodium spp.) causes nearly one million deaths annually and with the increase in mosquito resistance to drugs the existing anti-malaria strategies are inadequate in terms of the control efficiency. The introduction of genes that impair Plasmodium development into mosquito population is a new strategy for malaria control. The article reviews some recent advances in the research of transgenic mosquitoes, gene regulation mechanisms and the way by which the transgenic mosquitoes play their role in the control of malaria.

Key words: Transgenic mosquitoes, Malaria, Mechanism

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