关键词: 艾叶提取物, 毛囊蠕形螨, 杀螨率

Abstract: Objective To explore the effect of Folium artemisiae argyi crude extract in killing Demodex in vitro.Methods The mites were collected with adhesive cellophane tape and were randomly divided into alcoholic extract groups,water extract groups and control groups.The mites were observed in 4 h,8 h and 12 h respectively.Results Among the three different alcoholic extract groups,the death rate of Demodex folliculorum in 60% alcoholic extract group was higher than 70% and 80% alcoholic extract group in 4 h,8 h and 12 h,respectively.Among the four concentrations of 60% alcoholic extract group,there were no significant difference between 2 mg/ml and 3 mg/ml alcoholic extract of Folium artemisiae argyi.But the effect of killing Demodex of 2 mg/ml alcoholic extract was better than that of(1 mg/ml) and(0.5 mg/ml),and the death rate of the four concentration groups were all above 72.12%.With the laboratorial test confirmed,we demonstrated that the effect of killing Demodex of Folium artemisiae argyi was superior to the Stemona Root and the effect of killing Demodex in alcoholic extract groups of Folium artemisiae argyi was better than that of water extract groups.Conclusion Both the alcoholic extract groups and water extract groups of Folium artemisiae argyi have the effect on Demodex in vitro,and the former is better than the latter.In the groups of alcoholic extract of Folium artemisiae argyi,(it's) the(2 mg/ml) of 60% alcoholic extract group the most effective.The effect of Folium artemisiae argyi crude extract in killing Demodex in vitro is superior to Stemona Root.